Center for Neurogeneration
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Latest News

BBSRC ALERT 2014 award

Catherina Becker, David Lyons (both CNR) and Liz Patton (MRC HGU) have received a £520,000 major equipment grant from BBSRC through the Advanced Life Sciences Research Technology initiative (ALERT14) to establish an automated phenotypic (drug and genetic) screening platform for the UK zebrafish community. The initiative is co-funded by further support (£100,000) from Biogen Idec and the College of Medicine and Veterinary Medicine at the University of Edinburgh.

DFG Fellowship to Dr Daniel Wehner

Congratulations to Daniel Wehner, who was awarded a highly competitive research fellowship from the German Research Foundation DFG. Daniel, who recently joined CNR from Ulm, Germany, will investigate the role of the wnt signalling pathway in successful spinal cord regeneration in the zebrafish in the Becker Group.

EMBO Fellowship to Dr Marcos Cardozo

Congratulations to Marcos Cardozo, who was awarded a prestigious EMBO Long Term Fellowship to work in the Becker laboratory. Marcos, who recently joined CNR from Madrid, Spain, will investigate the role of dopamine during spinal cord development and regeneration in the zebrafish.

1 September 2014
MRC Grant for Super-Resolution Imaging to Brophy Lab

The Brophy lab has been awarded £765,438 from the Medical Research Council to study how the node of Ranvier is assembled.
The node is a crucial structure in the nervous system that is absolutely necessary for fast conduction of impulses in our nerves and which is disrupted in demyelinating diseases such as multiple sclerosis. The study will use state of the art microscopy in collaboration with the new Edinburgh Super Resolution Imaging Centre.
 

28 August 2014
Becker Group awarded BBSRC Grant

The Becker group have been awarded a £480k grant from the Biotechnology and Biological Sciences Research Council to investigate the regeneration of dopaminergic cells in the zebrafish brain. Adult zebrafish have an amazing capacity to repair injuries to their brain and spinal cord. In particular, there are so-called progenitor cells in the brain that can divide and thus generate new nerve cells. In mammals, including humans, such regeneration usually fails. Nerve cells that produce the chemical dopamine, an important modulator of brain activity, are particularly vulnerable to influences of toxins, aging and disease, such as Parkinson's disease which leads to life-long disability. The Becker group will determine whether dopamine producing nerve cells are regenerated in the adult zebrafish and whether this repairs leads to recovery of lost functions. This will help them determine at a fundamental level how it is possible to replace lost nerve cells in the adult and fully wired nervous system. 

28 August 2014
Muscular Dystrophy Campaign grant success

Congratulations to Prof. Tom Gillingwater from the CIP and Prof. Catherina Becker from the CNR who have been awarded a 2 year project grant from the Muscular Dystrophy Campaign.

Working with mouse and zebrafish models of spinal muscular atrophy (SMA) will allow to understand the molecular basis of why some motor neurons are particularly vulnerable in the disease, whereas others are resistant to the disease.
This will hopefully lead to the identification of pathways that can act as novel therapeutic targets for the treatment of SMA and related neurodegenerative conditions.

The Muscular Dystrophy Campaign supports excellent research projects, aiming to find treatments and cures for muscular dystrophy and related neuromuscular conditions.

31 July 2014
Karolina Mysiak wins Poster Prize

Karolina Mysiak has won the $500 Poster Prize for her poster: Serotonin promotes motor neuron development and adult regeneration in zebrafish
at the "Development, Functions and Disorders of the Nervous System" Joint Meeting of the 20th Biennial Meeting of the International Society for Developmental Neuroscience and the 5th Annual NeuroDevNet Brain Development Conference in Montreal, Canada.

We are very proud!

 

29 July 2014
Dr. Dirk Sieger, Congratulations!

Dr Dirk Sieger has been awarded a highly competitive Cancer Research UK Career Establishment Award. These prestigious awards offer up to 6 years of funding for early career PIs to establish their own line of research. Dr Sieger and his team will study the interaction of brain specific immune cells, known as microglia, and brain tumours. With a special focus on glioblastoma, the most aggressive type of brain tumour, they aim to understand how microglia are controlled within the tumour environment and intend to identify the underlying molecular mechanisms. Congratulations!

 

23 July 2014
Grant success for the Becker group

The Becker group was awarded a £600k project grant from the BBSRC to investigate the role of the descending dopaminergic projection in spinal development and regeneration in the zebrafish. This is a collaboration with Prof Keith Sillar at the University of St. Andrews. Congratulations!

23 July 2014
Bridie Nelson is fundraising to support Lyons Lab

Bridie Nelson decided to write a fundraising poetry book when her son was diagnosed with multiple sclerosis (MS) at the age of 24. Bridie is helping to raise money for research projects that will, in the future, benefit many of those with this and other neurological conditions. Together with her son chose to support Dr David Lyons and his team at the Centre for Neuroregeneration, who are doing such valuable research into myelin repair. Bridie's collection of short poems will suit every mood and all profits made from the sale of this book will be donated to Lyons Lab.

Together we can help to make this happen.'Whispers of the Soul' by Bridie Nelson can be bought on Amazon here.

 

21 March 2014
Dr. Michell Reimer
, Congratulations!

Dr. Michell Reimer has been offered a junior group leader position with tenure track at the CRTD / DFG-Center for Regenerative Therapies Dresden - Cluster of Excellence, TU Dresden Germany. The Becker lab is sad to see Michell leave but very happy that he managed to secure this excellent position to set up his own research group and wishes him all the best and success for the future.

 

21 March 2014
Dr. HongYan Zhang and Dr. Dirk Sieger, Awarded from the Royal Society Research Grant

Dr HongYan Zhang and Dr Dirk Sieger have been given awards from the Royal Society Research Grant. Dr. Zhang has been awarded £14,416, this grant will allow acquiring equipment to enable fine dissections on the spinal cord and perform visually guided patch recordings on identified neurons. Dr. Sieger received £13,000 grant, this will go towards obtaining specialized equipment needed to establish a zebrafish model to study microglia glioma interactions in vivo.

 

20 March 2014
Congratulations to the CNR PhD Student winners at Neuroscience Day 2014

We are honored to announce that the Centre has won 4 of the 7 poster prizes at the Neuroscience Day 2014: Yujie Yang (Becker Lab) and Sigrid Mensch (Lyons Lab), as runners up; Rafael Almeida (Lyons Lab), as winner of the Development and Regeneration theme; and Melissa Cizeron (Grant Lab), as winner of the Cellular and Molecular theme and overall best poster winner. Congratulations everyone!

 

14 February 2014
Congratulations to fundraising couple

A couple pledge their civil partnership gifts to our Centre for Neuroregeneration to support research into neurodegenerative diseases. Paul Knott and Robert Smith's generosity is in memory of Paul's mother, Bobbie, who had multiple sclerosis. Anyone can donate via the Justgiving page http://www.justgiving.com/Knott-Smith

 

08 January 2014
Dr. David Lyons awarded Senior Research Fellowship

Dave Lyons of the Centre for Neuroregeneration has been awarded a highly competitive Senior Research Fellowship from the Wellcome Trust. Dave will be developing his very successful programme on myelination with a strong emphasis on live imaging and forward genetics in the zebrafish.

 

 


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